Isolation and 2D-NMR analysis of methylation impurity formed in the condensation/reduction reaction in the synthesis of berberine

ZHANG Xiangming, ZHAO Zongmin, ZHANG Xiaojin, GU Zhiguo

Shanghai Medical & Pharmaceutical Journal ›› 2024, Vol. 45 ›› Issue (9) : 118-121.

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Shanghai Medical & Pharmaceutical Journal ›› 2024, Vol. 45 ›› Issue (9) : 118-121.
PHARMACEUTICAL R&D

Isolation and 2D-NMR analysis of methylation impurity formed in the condensation/reduction reaction in the synthesis of berberine

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