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Influence of postoperative prescription of traditional Chinese medicine for breast cancer combined with conventional western medicine treatment on traditional Chinese medicine syndrome score and quality of life of postoperative patients with breast cancer
HUANG Shuangqing, LI Tian, WANG Xiaoting, ZHU Lingyi, ZHANG Weihong
Shanghai Medical & Pharmaceutical Journal ›› 2023, Vol. 44 ›› Issue (12) : 31-33.
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Influence of postoperative prescription of traditional Chinese medicine for breast cancer combined with conventional western medicine treatment on traditional Chinese medicine syndrome score and quality of life of postoperative patients with breast cancer
({{custom_author.role_en}}), {{javascript:window.custom_author_en_index++;}}Objective: To observe the effect of postoperative prescription of traditional Chinese medicine(TCM) for breast cancer on the basis of conventional western medicine treatment on TCM symptoms and quality of life in patients with breast cancer. Methods: One hundred and ninety-seven cases of postoperative patients with breast cancer diagnosed and treated in Breast Surgery Department of Baoshan Branch of Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai from July 2020 to July 2021 were retrospectively analyzed, and according to the treatment scheme, and were divided into a treatment group with 99 cases and a control group with 98 cases. The control group was treated with conventional western medicine; on the basis of conventional western medicine treatment, the treatment group began to take Chinese medicine after breast cancer surgery one month after surgery, and six months was one course of treatment, and the treatment had two courses. The TCM syndrome score, TCM symptom efficacy evaluation, and life quality of the two groups after two courses of treatment were compared. Results: After treatment, the score of TCM syndrome in the treatment group was significantly lower than that in the control group(P<0.05); the total effective rate of symptomatic efficacy of TCM was 90.91%(90/99), which was higher than that 69.39% in the control group(68/98, P<0.05). The scores of WHOQOL-BREF scale in the fields of physiology, psychology, social relations, and environment in the treatment group increased(P<0.05), and the treatment group was significantly higher than the control group(P<0.05). Conclusion: Postoperative prescription of TCM for breast cancer combined with conventional western medicine treatment can significantly improve the clinical symptoms of postoperative patients with breast cancer, improve the quality of life, and the TCM syndrome is effective.
breast cancer / postoperative prescription of traditional Chinese medicine for breast cancer / quality of life / traditional Chinese medicine syndrome point {{custom_keyword}} /
表1 两组临床一般资料比较 [n（%）] |
| 一般资料 | 治疗组（n=99） | 对照组（n=98） | P值 |
|---|---|---|---|
| 年龄/岁 | 0.25 | ||
| ≤35 | 4（4.04） | 7（7.14） | |
| 35~50 | 20（20.20） | 27（27.55） | |
| >50 | 75（75.76） | 64（65.31） | |
| 学历 | 0.55 | ||
| 小学及以下 | 23（23.23） | 26（26.53） | |
| 初中 | 37（37.37） | 32（32.65） | |
| 高中 | 32（32.32） | 28（28.57） | |
| 本科及以上 | 7（7.07） | 12（12.24） | |
| 手术方式 | 0.48 | ||
| 全乳切除 | 64（64.65） | 68（96.39） | |
| 保乳 | 35（35.35） | 30（30.61） | |
| 病例类型 | 0.20 | ||
| 浸润性导管癌 | 56（56.56） | 64（65.31） | |
| 其他类型 | 43（43.43） | 34（34.69） | |
| 肿瘤分期 | 0.29 | ||
| T1 | 68（68.69） | 69（70.41） | |
| T2 | 23（23.23） | 26（26.53） | |
| T3 | 8（8.08） | 3（3.06） | |
| 淋巴结分期 | 0.50 | ||
| N0 | 47（47.47） | 45（45.92） | |
| N1 | 38（38.38） | 39（39.80） | |
| N2 | 10（10.10） | 6（6.12） | |
| N3 | 4（4.04） | 8（8.16） |
表2 两组治疗前后中医证候积分比较 （ |
| 组别 | 例数 | 中医证候积分 | t值 | P值 | |
|---|---|---|---|---|---|
| 治疗前 | 治疗后 | ||||
| 治疗组 | 99 | 22.81±2.09 | 9.04±4.45 | 26.04 | <0.001 |
| 对照组 | 98 | 22.77±1.98 | 12.40±5.99 | 15.92 | <0.001 |
| t值 | -0.20 | -6.40 | |||
| P值 | 0.84 | <0.001 | |||
表3 两组中医症状疗效比较 [n（%）] |
| 组别 | 例数 | 显效 | 有效 | 无效 | 总有效 |
|---|---|---|---|---|---|
| 治疗组 | 99 | 48（48.48） | 42（42.42） | 9（9.09） | 90（90.91） |
| 对照组 | 98 | 35（35.71） | 33（33.67） | 30（30.61） | 68（69.39） |
| χ2值 | 14.42 | ||||
| P值 | 0.001 |
表4 两组生活质量评分比较（ |
| 组别 | 生理领域 | 心理领域 | 社会关系 | 环境领域 |
|---|---|---|---|---|
| 治疗组（n=99） | ||||
| 治疗前 | 11.46±2.76 | 11.74±2.51 | 11.49±2.51 | 11.33±2.76 |
| 治疗后 | 12.39±2.60a | 12.50±2.65a | 12.32±2.48a | 12.14±2.80a |
| 对照组（n=98） | ||||
| 治疗前 | 9.56±1.89 | 9.39±1.95 | 12.29±2.48 | 12.10±2.79 |
| 治疗后 | 10.58±1.61a | 11.12±1.96a | 11.28±2.12 | 10.40±1.94 |
| t值治疗后 | 7.42 | 7.3 | 5.71 | 7.08 |
| P值治疗后 | <0.001 | <0.001 | <0.001 | <0.001 |
| 注：与同组治疗前比较，aP<0.05。 |
| [1] |
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [2] |
The purpose of the present article was to investigate the health related quality of life (QoL) of young women with breast cancer.For the purposes of this article, we reviewed the literature via the electronic databases Pubmed, Scopus and Google Scholar. Key words used were breast cancer, young women, health related quality of life, and quality of life.Young women reported fatigue, pain in the breast and hand problems with lymphedema as the most frequent physical effects of treatment. Other physical problems were the not periodic and painful menses, vaginal dryness and loss of libido. Many young women had depressive symptoms such as depressed mood, helplessness, hopelessness, sleep loss, psychomotor retardation and disorders of appetite. There were often concerns about the health monitoring and self-image, while they were anxious if they will have a baby in the future or if they can nurture the existing ones. Many problems arose in the career of young women. They faced discrimination in the labor supply and/or layoff because they were considered unable to do their job effectively. In addition, they reported isolation problems and feeling different from other women of similar age.Young women consider that their healthrelated QoL is worse compared with older women. Young women worry about their future, with particular reference to their role as mothers and especially to children-bearing. The free screening and non-exclusion of young women is particularly important for breast cancer prevention and women's well-being.
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [3] |
中国抗癌协会乳腺癌专业委员会. 中国抗癌协会乳腺癌诊治指南与规范(2021)[J]. 中国癌症杂志, 2021, 31(10): 954-1040.
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [4] |
中华中医药学会乳腺病防治协作工作委员会. 乳腺癌分期辨证规范(试行)[J]. 上海中医药杂志, 2010, 44(1): 4-5.
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [5] |
郑筱萸. 中药新药临床指导原则[S]. 北京: 中国医药科技出版, 2002: 216.
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [6] |
祝亚男, 汪永坚, 陈晓洁, 等. 《乳腺癌中医症状分级量化评价表》的制定与应用[J]. 护理与康复, 2016, 15(10): 980-982.
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [7] |
申旭波, 刘方苇, 熊世敏, 等. 基于 WHOQOL-BREF量表的中老年男性生命质量现况分析[J]. 现代预防医学, 2018, 45(6): 1118-1121.
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [8] |
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [9] |
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [10] |
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [11] |
陆徳铭工作室. 陆徳铭学术经验撷英[M]. 上海: 上海中医药大学出版社, 2010: 46-48.
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| [12] |
刘静. 陆德铭教授运用扶正祛邪法治疗乳腺癌经验[J]. 中医学报, 2016, 31(4): 470-473.
{{custom_citation.content}}
{{custom_citation.annotation}}
|
| {{custom_ref.label}} |
{{custom_citation.content}}
{{custom_citation.annotation}}
|
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